The following is a summary of some of the clinical studies that were conducted using cold laser to treat cartilage regeneration. These studies are presented here to demonstrate the wide uses of a cold lasers in the treatment of different medical conditions.

Histological and clinical responses of articular cartilage to low-level laser therapy: Experimental study

I. Ruiz Calatrava1 , J. M. Santisteban Valenzuela1, R. J. Gómez-Villamandos1, J. I. Redondo1, J. C. Gómez-Villamandos1 and I. Avila Jurado1 (1) Department of Veterinary Clinical Pathology-Surgery, Faculty of Veterinary Medicine, University of Cordoba, Avda. Medina Azahara, 9, 14005 Córdoba, Spain

Received: 30 July 1996 Revised: 18 September 1996 Accepted: 20 November 1996

This study was carried out to evaluate the effects of low-level laser irradiation on experimental lesions of articular cartilage. A standard lesion was practiced on the femoral trochlea of both hind-limbs of 20 clinically normal Californian rabbits. These animals were divided into two groups of 10 individuals each, depending on the laser equipment used for treatment.

One group was treated with He-Ne laser (8 J cm-2, 632.8 nm wavelength) and the other with infra-red (IR) laser (8 J cm-2, 904 nm wavelength). In both groups, five points of irradiation to the right limb alone were irradiated per session for a total of 13 sessions, applied with an interval of 24 h between sessions. These points were the following: left and right femoral epicondyles, left and right tibial condyles and the centre of articulation. The distance between these points was approximately 1 cm.

The untreated left limb was left as a control. During treatment, extension angle and periarticular thickness were considered. At the end of the treatment, samples were collected for histopathologi-cal study and stained with: Haematoxylin-Eosin, PAS and Done. The results show a statistically higher anti-inflammatory capacity of the IR laser (p < 0.0001). The functional recovery was statistically similar for both treatments (p < 0.176). Histological study showed, at the end of the treatment, hyaline cartilage in the IR group, fibrocartilage in the He-Ne group and granulation tissue in the control limbs. Clinical and histological results indicated that this laser treatment had a clear anti-inflammatory effect that provided a fast recuperation and regeneration of the articular cartilage.