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Neuropathy and Cold Laser Therapy

Kalon Prensky's picture
Tue, 01/03/2017 - 11:44 -- Kalon Prensky

Peripheral Neuropathy is a growing issue among the aging population and current research indicates that it can be treated with cold laser therapy

What it Peripheral Neuropathy?

Peripheral nerves carry information to and from the brain. These nerves also carry signals to and from the spinal cord to the rest of the body. Peripheral neuropathy means these nerves have been compromised in some way and no longer work properly. Peripheral neuropathy can be seen as damage to a single nerve or damage to a group of nerves. Peripheral Neuropathy, or the numbness and pain caused by nerve damage in the hands and feet is attributed to a number of factors. The top factor has to do with the supply of blood to the nerve(s) that are affected. Nerve fibers are responsible for pain conduction and when they are damaged they can cause a loss of sensation, which creates a burning and tingling sensation for the patient. This is most commonly seen in the feet and legs, but can also occur in the hands and arms. 

Dr. Bradley Gipson, DPM wrote:

"Most treatments currently in use for neuropathy are geared towards treating the symptoms and not to cure the problem. These treatments help lessen the symptoms to make the disease more manageable for the patient; however, they usually involve prescription medications that mask the disease rather than treating it.

Recent research has shown that Cold Laser Therapy can help treat the underlying causes of neuropathy and help with symptom management. Cold Laser Therapy helps by actually stimulating microcirculation around the nerve fibers, which increases blood flow to the nerves and helps to heal and reduce neuropathic pain. Laser light energy penetrates the skin and stimulates increased oxygen on a cellular level. This increase in microcirculation around the nerve has been shown to help regenerate fibers and help heal peripheral nerves. Cold Laser Therapy is painless and has been proven to decrease neuropathy, decrease inflammation and aide in the healing of wounds and tendons."

The following study excerpt was authored by:
Kerry Zang, DPM, Janna Kroleski, DPM, Shahram Askari, DPM,
and Sanford Kaner, DPM

"The biological effect of coherent laser irradiation on cells is termed photobiomodulation. All light is radiation energy that is measured in discrete units called photons and its effect on cellular components is mediated by biological photo-acceptor molecules that are found in a variety of cellular components throughout the human body. Two cellular components in particular that have been identified are cytochrome c oxidase, which is part of the electron transport chain of mitochondria, and porphyrins, which are found in the eukaryotic cell membrane. Cytochrome c oxidase is a multi-component membrane protein, which contains a binuclear copper center (CuA) and a heme binuclear center (a3-CuB). Cytochrome c oxidase facilitates the transfer of electrons from cytochrome c to oxygen, driving oxidative phosphorylation. Researchers believe low-level laser stimulation of cytochrome c oxidase accelerates the transfer rate of electrons and makes more electrons available for the reduction of dioxygen. Functional changes in the terminal enzyme increase the membrane potential and proton gradient, changing mitochondrial optical properties and increasing the rate of ADP/ATP exchange.

Several classes of non-opioid analgesics act as specific inhibitors of COX-2 and prevent eicosanoid formation. In vitro and in vivo studies have shown that laser therapy reduces PGE2, interleukin-1α and TNF-α by inhibiting COX-2. One hypothesis is that laser therapy influences the intracellular redox state by modulating the transcription factor nuclear factor kappa B, which undergoes phosphorylation and ubiquitination, and promotes proteolytic degradation of IKB-a under oxidative stress. A shift in the intracellular redox state may affect the cascade responsible for regulating COX-2 expression, thereby suppressing the synthesis of pro-inflammatory cytokines.

Researchers have shown that low-level laser therapy upregulates VEGF, which promotes neovascularization. Enhanced microcirculation may contribute to the stabilization of cell metabolism by increasing cellular nutrient and oxygen concentrations.

Eleven patients diagnosed with small fiber neuropathy via epidermal nerve fiber density testing underwent 12 low-level laser therapy treatments (10 minutes per extremity) three times a week for four weeks........ For each participant in the study, we reported an improvement in the overall perceived pain rating. Study participants exhibited an average improvement in neuropathic pain of 75 percent."

Some patients are seeking out a doctor or therapist who work with with cold lasers aka low level lasers. Others are looking for the perfect cold laser device that they can safely and easily use in the comfort of their own home. The Scalar Wave Laser is a super safe, over the counter (OTC), FDA cleared, portable, hand-held cold laser that is easy to use, and can be purchased and used by home consumers to increase blood circulation and alleviate pain and Arthritis.

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The Scalar Wave Laser System is indicated for temporary relief of minor muscle and joint pain, arthritis and muscle spasm, relieving stiffness, promoting relaxation of muscle tissue, and temporarily increasing local blood circulation. The System is not intended to diagnose, treat, cure, mitigate, or prevent disease. If you have a disease or medical condition, consult with your physician or health practitioner before using the Scalar Wave Laser. Use only as directed. No statements made here are intended as medical claims or advice and is for informational purposes only. Results may vary from person to person. 
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